Arterial Disease, Myocardial Ischemia and Structural Damage

Introduction

Program 2 focuses on cardiovascular alterations that can cause premature death and disability either by inducing secondary myocardial remodeling or through rupture of cardiovascular structures, thromboembolic events and infection.

These alterations include the following: arterial diseases such as ischemic heart disease, the first cause of death and loss of quality of life years throughout the world; aortic disease, which results in acute complications with high mortality; and structural diseases of the heart such as acquired valve disease and congenital heart abnormalities.

Lines of research

The program is organized into three major research lines:

1) Myocardial Ischemia and Reperfusion. The objective of this line is to reduce the loss of quality of life years and social impact of ischemic heart disease by generating knowledge to prevent plaque progression and complications leading to myocardial ischemia and to reduce myocardial damage when myocardial ischemia occurs.

2) Aortic Valve Diseases. The central aims of this line are to identify the biomolecular and biomechanical mechanisms that determine aortic dilatation and complications and to develop accurate methods to define predictors of complications and new treatment strategies to improve disease progression and survival.

3) Valvular and Congenital Heart Disease. The objective of this line is to increase our knowledge of the etiology, pathophysiology and natural history of valvular and congenital heart disease, identifying predictors of poor outcome, and improving the role of imaging in this setting, with the ultimate goal of designing therapeutic strategies to reduce morbidity.

Program coordinators

David García-Dorado, MD, PhD

Cardiology Department

Vall d’Hebron University Hospital and Research Institute

Coordinator Vascular Biology and Metabolism Area

Pg Vall d’Hebron 119-129

08035 Barcelona

dgdorado@vhebron.net
                  

Alberto San Roman; MD, PhD

Cardiology Department

Hospital Universitario de Valladolid,

Av. Ramón y Cajal, 3,

47002 Valladolid

asanroman@secardiologia.es

Research groups

Jefe de GrupoInstitución consorciadaProvinciaDetalles

Andrés García, Vicente

Fundación Centro Nacional de Investigaciones Cardiovasculares Madrid Group info

Badimon Maestro, Lina

Instituto de Investigacion del Hospital de la Santa Cruz y San Pablo Barcelona Group info

Bayés Genís, Antonio

Fundación Instituto de Investigacion Germans Trias i Pujol Barcelona Group info

Blanco Colio, Luis Miguel

Instituto de Investigación Sanitaria Fundación Jiménez Díaz Madrid Group info

Bosca Gomar, Lisardo

Agencia Estatal Consejo Superior de Investigaciones Científicas Madrid Group info

Brugada Terradellas, Ramon

Fundación Instituto de Investigacion Biomédica de Girona Girona Group info

Cinca Cuscullola, Juan M.

Instituto de Investigacion del Hospital de la Santa Cruz y San Pablo Barcelona Group info

Delgado Jiménez, Juan Francisco

Servicio Madrileño de Salud Madrid Group info

Fernández-Avilés Díaz, Francisco

Servicio Madrileño de Salud Madrid Group info

García Pavía, Pablo

Servicio Madrileño de Salud Madrid Group info

García-Dorado García, David

Fundación Hospital Universitario Vall d´Hebron - Institut de Recerca (VHIR) Barcelona Group info

González Juanatey, Jose Ramón

Servicio Gallego de Salud A Coruña Group info

Ibáñez Cabeza, Borja

Instituto de Investigación Sanitaria Fundación Jiménez Díaz Madrid Group info

López-Sendon Hentschel, José Luis

Servicio Madrileño de Salud Madrid Group info

Marrugat de la Iglesia, Jaume

Consorci Mar Parc Salut de Barcelona Barcelona Group info

Martínez González, Jose

Agencia Estatal Consejo Superior de Investigaciones Científicas Barcelona Group info

Mayor Menéndez, Federico

Universidad Autónoma de Madrid Madrid Group info

Mont Girbau, Josep Lluis

Instituto de Investigaciones Biomédicas August Pi i Sunyer Barcelona Group info

Ordóñez Fernández, Antonio

Fundación Pública Andaluza para la Gestion de la Investigacion en Salud de Sevilla Sevilla Group info

Páramo Fernández, José Antonio

Universidad de Navarra Navarra Group info

Pompa Mínguez, José Luis de la

Fundación Centro Nacional de Investigaciones Cardiovasculares Madrid Group info

Redondo Moya, Juan Miguel

Fundación Centro Nacional de Investigaciones Cardiovasculares Madrid Group info

Rivera Otero, José Miguel

Fundación para la Investigación del Hospital la Fe Valencia Group info

Salaices Sánchez, Mercedes

Universidad Autónoma de Madrid Madrid Group info

San Román Calvar, José Alberto

Hospital Clínico Universitario de Valladolid Valladolid Group info

Sánchez Fernández, Pedro Luis

Fundación Instituto de Estudios de Ciencias de la salud de Castilla y León Salamanca Group info

Sánchez Madrid, Francisco

Universidad Autónoma de Madrid Madrid Group info

Jiménez Navarro, Manuel Francisco  

Fundación Pública Andaluza para la Investigacion de Málaga en Biomedicina y Salud Málaga Group info

Valdés Chavarri, Mariano

Fundación para la Formacion e Investigacion Sanitarias de la Región de Murcia Murcia Group info

Vázquez Cobos, Jesús María

Fundación Centro Nacional de Investigaciones Cardiovasculares Madrid Group info

Zamorano Gómez, José Luis

Servicio Madrileño de Salud Madrid Group info